Clinical usefulness of a urine dipstick to detect ethyl glucuronide (EtG): A quantitative clinical study in healthy young female volunteers

The metabolite of ethanol, ethyl glucuronide (EtG), reflects alcohol intake longer than ethanol and is used as a biomarker in clinical settings to detect use. We aimed assess the usefulness low-to-moderate setting validate new urine EtG dipstick. A three-way, open, cross-over trial was conducted. Data were collected from January June 2019. Among 12 healthy female volunteers, we quantified dipstick following either one, two or four units alcohol. Main outcomes concentrations serum, creatinine serum. determined dichotomously by dipsticks at different thresholds mass spectrometry gold standard. quantifiable up 24 hours after intake. In some individual cases, 72 low concentrations. detected hours. At 1000 1500 ng/mL, had specificity 100% (both), while sensitivity 84% 69%, respectively. insufficient support screening purpose this